

The information can be easily sorted, filtered or edited. With an integrated spreadsheet with over 100,000 rows, MedCalc is capable of reading and displaying detailed data imported from Excel, SPSS, Dbase, Lotus or extracted from SYLK, DIF or text files. It provides the necessary tools and features for performing Receiver Operating Characteristic curve analysis, data plotting, Bablok and Deming regression and more. MedCalc is designed to meet the requirements of biomedical researchers with respect to the statistical analysis of large datasets. (Version 22.Statistical software for biomedical research with a rich set of functions, graph types and an advanced module for performing ROC graph analysis.

The P-value is the area of the t distribution with n 1 + n 2 − 2 degrees of freedom, that falls outside ± t (see Values of the t distribution table). The significance level, or P-value, is calculated using the t-test, with the value t calculated as: The standard error se of the difference between the two means is calculated as: Where s 1 and s 2 are the standard deviations of the two samples with sample sizes n 1 and n 2. The program first calculates the pooled standard deviation s:

Sample size: the number of observations in the sample.Standard deviation: the observed standard deviation.The null hypothesis is the hypothesis that the difference is 0. The P-value is the probability of obtaining the observed difference between the samples if the null hypothesis were true. A significance value (P-value) and 95% Confidence Interval (CI) of the difference is reported.

This procedure calculates the difference between the observed means in two independent samples.
